72 search results - page 4 / 15 » The impact of sample imbalance on identifying differentially... |
BMCBI
2004
13 years 7 months ago
2004
Background: High-density oligonucleotide microarray technology enables the discovery of genes that are transcriptionally modulated in different biological samples due to physiolog...
BMCBI
2006
13 years 8 months ago
2006
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
BMCBI
2007
13 years 8 months ago
2007
Background: Classification studies using gene expression datasets are usually based on small numbers of samples and tens of thousands of genes. The selection of those genes that a...
BMCBI
2010
13 years 5 months ago
2010
Background: With the expansion of public repositories such as the Gene Expression Omnibus (GEO), we are rapidly cataloging cellular transcriptional responses to diverse experiment...
BMCBI
2006
13 years 8 months ago
2006
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...