Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...
Background: The chemical property and biological function of a protein is a direct consequence of its primary structure. Several algorithms have been developed which determine ali...
Kshitiz Gupta, Dina Thomas, S. V. Vidya, K. V. Ven...
Background: With the explosion of microarray studies, an enormous amount of data is being produced. Systematic integration of gene expression data from different sources increases...
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...