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BMCBI
2010
86views more  BMCBI 2010»
13 years 8 months ago
Reaction graph kernels predict EC numbers of unknown enzymatic reactions in plant secondary metabolism
Background: Understanding of secondary metabolic pathway in plant is essential for finding druggable candidate enzymes. However, there are many enzymes whose functions are not yet...
Hiroto Saigo, Masahiro Hattori, Hisashi Kashima, K...
BMCBI
2007
160views more  BMCBI 2007»
13 years 8 months ago
Optimization based automated curation of metabolic reconstructions
Background: Currently, there exists tens of different microbial and eukaryotic metabolic reconstructions (e.g., Escherichia coli, Saccharomyces cerevisiae, Bacillus subtilis) with...
Vinay Satish Kumar, Madhukar S. Dasika, Costas D. ...
BMCBI
2008
142views more  BMCBI 2008»
13 years 8 months ago
Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...
BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Comparative analyses of bidirectional promoters in vertebrates
Background: Orthologous genes with deep phylogenetic histories are likely to retain similar regulatory features. In this report we utilize orthology assignments for pairs of genes...
Mary Qu Yang, James Taylor, Laura Elnitski
CORR
2010
Springer
177views Education» more  CORR 2010»
13 years 8 months ago
Supervised Random Walks: Predicting and Recommending Links in Social Networks
Predicting the occurrence of links is a fundamental problem in networks. In the link prediction problem we are given a snapshot of a network and would like to infer which interact...
Lars Backstrom, Jure Leskovec