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GI
2009
Springer
14 years 5 days ago
Massively-Parallel Simulation of Biochemical Systems
: Understanding biological evolution prompts for a detailed understanding of the realized phenotype. Biochemical and gene regulatory dynamics are a cornerstone for the physiology o...
Jens Ackermann, Paul Baecher, Thorsten Franzel, Mi...
RECOMB
2005
Springer
14 years 7 months ago
Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Cathal Seoighe, Konrad Scheffler
BMCBI
2007
103views more  BMCBI 2007»
13 years 7 months ago
Dynamic simulation of regulatory networks using SQUAD
Background: The ambition of most molecular biologists is the understanding of the intricate network of molecular interactions that control biological systems. As scientists uncove...
Alessandro Di Cara, Abhishek Garg, Giovanni De Mic...
WCE
2007
13 years 8 months ago
A Patch-by-Patch Shape Matching Procedure for Rigid Body Docking
Abstract—Docking simulates molecular interactions. Protein - protein docking, owing to the sizes of molecules, is a very challenging problem. As the number of degrees of freedom ...
Vipin K. Tripathi
BMCBI
2010
141views more  BMCBI 2010»
13 years 7 months ago
BioPhysConnectoR: Connecting Sequence Information and Biophysical Models
Background: One of the most challenging aspects of biomolecular systems is the understanding of the coevolution in and among the molecule(s). A complete, theoretical picture of th...
Franziska Hoffgaard, Philipp Weil, Kay Hamacher