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» The molecular modeling toolkit: A new approach to molecular ...
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ANSS
2006
IEEE
14 years 1 months ago
iSimBioSys: A Discrete Event Simulation Platform for 'in silico' study of biological systems
With the availability of huge databases cataloguing the various molecular “parts” of complex biological systems, researchers from multiple disciplines have focused on developi...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...
RECOMB
2003
Springer
14 years 7 months ago
Physical network models and multi-source data integration
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...
Chen-Hsiang Yeang, Tommi Jaakkola
IPPS
2008
IEEE
14 years 2 months ago
Overcoming scaling challenges in biomolecular simulations across multiple platforms
NAMD† is a portable parallel application for biomolecular simulations. NAMD pioneered the use of hybrid spatial and force decomposition, a technique now used by most scalable pr...
Abhinav Bhatele, Sameer Kumar, Chao Mei, James C. ...
BMCBI
2008
83views more  BMCBI 2008»
13 years 7 months ago
Models of deletion for visualizing bacterial variation: an application to tuberculosis spoligotypes
Background: Molecular typing methods are commonly used to study genetic relationships among bacterial isolates. Many of these methods have become standardized and produce portable...
Josephine F. Reyes, Andrew R. Francis, Mark M. Tan...
BMCBI
2002
214views more  BMCBI 2002»
13 years 7 months ago
Automated modelling of signal transduction networks
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
Martin Steffen, Allegra Petti, John Aach, Patrik D...