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CIBCB
2005
IEEE
14 years 1 months ago
Toward Protein Structure Analysis with Self-Organizing Maps
- Establishing structure-function relationships on the proteomic scale is a unique challenge faced by bioinformatics and molecular biosciences. Large protein families represent nat...
Lutz Hamel, Gongqin Sun, Jing Zhang
ASPLOS
2009
ACM
14 years 2 months ago
Architectural implications of nanoscale integrated sensing and computing
This paper explores the architectural implications of integrating computation and molecular probes to form nanoscale sensor processors (nSP). We show how nSPs may enable new compu...
Constantin Pistol, Christopher Dwyer, Alvin R. Leb...
CMSB
2009
Springer
13 years 11 months ago
Control Strategies for the Regulation of the Eukaryotic Heat Shock Response
Abstract. Elevated temperatures cause proteins in living cells to misfold. They start forming larger and larger aggregates that can eventually lead to the cell's death. The he...
Elena Czeizler, Eugen Czeizler, Ralph-Johan Back, ...
BMCBI
2010
112views more  BMCBI 2010»
13 years 7 months ago
A parameter-adaptive dynamic programming approach for inferring cophylogenies
Background: Coevolutionary systems like hosts and their parasites are commonly used model systems for evolutionary studies. Inferring the coevolutionary history based on given phy...
Daniel Merkle, Martin Middendorf, Nicolas Wieseke
RECOMB
2010
Springer
14 years 2 months ago
On the Genealogy of Asexual Diploids
Given molecular genetic data from diploid individuals that, at present, reproduce mostly or exclusively asexually without recombination, an important problem in evolutionary biolog...
Fumei Lam, Charles H. Langley, Yun S. Song