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BMCBI
2010
151views more  BMCBI 2010»
13 years 9 months ago
CCRaVAT and QuTie - enabling analysis of rare variants in large-scale case control and quantitative trait association studies
Background: Genome-wide association studies have been successful in finding common variants influencing common traits. However, these associations only account for a fraction of t...
Robert Lawrence, Aaron G. Day-Williams, Katherine ...
BMCBI
2008
106views more  BMCBI 2008»
13 years 9 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
BMCBI
2008
78views more  BMCBI 2008»
13 years 8 months ago
Genome Environment Browser (GEB): a dynamic browser for visualising high-throughput experimental data in the context of genome f
Background: There is accumulating evidence that the milieu of repeat elements and other nongenic sequence features at a given chromosomal locus, here defined as the genome environ...
Derek Huntley, Y. Amy Tang, Tatyana B. Nesterova, ...
CN
2008
106views more  CN 2008»
13 years 8 months ago
Efficient virtual-backbone routing in mobile ad hoc networks
Since the physical topology of Mobile Ad hoc Networks (MANETs) is generally unstable, an appealing approach is the construction of a stable and robust virtual topology or backbone...
Jamal N. Al-Karaki, Ahmed E. Kamal
BMCBI
2006
111views more  BMCBI 2006»
13 years 8 months ago
SIMMAP: Stochastic character mapping of discrete traits on phylogenies
Background: Character mapping on phylogenies has played an important, if not critical role, in our understanding of molecular, morphological, and behavioral evolution. Until very ...
Jonathan P. Bollback