Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Background: Serial analysis of gene expression (SAGE) is used to obtain quantitative snapshots of the transcriptome. These profiles are count-based and are assumed to follow a Bin...
We address the issue of judging the significance of rare events as it typically arises in statistical naturallanguage processing. We first define a general approach to the problem...
How to efficiently discard potentially uninteresting rules in exploratory rule discovery is one of the important research foci in data mining. Many researchers have presented algor...
Pattern discovery techniques, such as association rule discovery, explore large search spaces of potential patterns to find those that satisfy some user-specified constraints. Due...