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BMCBI
2006
142views more  BMCBI 2006»
13 years 7 months ago
Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with
Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...
Angela Re, Davide Corà, Alda Maria Puliti, ...
BMCBI
2007
122views more  BMCBI 2007»
13 years 7 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2005
97views more  BMCBI 2005»
13 years 7 months ago
Evolutionary distance estimation and fidelity of pair wise sequence alignment
Background: Evolutionary distances are a critical measure in comparative genomics and molecular evolutionary biology. A simulation study was used to examine the effect of alignmen...
Michael S. Rosenberg
ICDM
2009
IEEE
145views Data Mining» more  ICDM 2009»
13 years 5 months ago
Significance of Episodes Based on Minimal Windows
Discovering episodes, frequent sets of events from a sequence has been an active field in pattern mining. Traditionally, a level-wise approach is used to discover all frequent epis...
Nikolaj Tatti
BMCBI
2010
196views more  BMCBI 2010»
13 years 4 months ago
Content-based microarray search using differential expression profiles
Background: With the expansion of public repositories such as the Gene Expression Omnibus (GEO), we are rapidly cataloging cellular transcriptional responses to diverse experiment...
Jesse M. Engreitz, Alexander A. Morgan, Joel Dudle...