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BMCBI
2007
114views more  BMCBI 2007»
13 years 10 months ago
Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
Xiaohua Hu, Fang-Xiang Wu
BMCBI
2008
138views more  BMCBI 2008»
13 years 10 months ago
Combining transcriptional datasets using the generalized singular value decomposition
Background: Both microarrays and quantitative real-time PCR are convenient tools for studying the transcriptional levels of genes. The former is preferable for large scale studies...
Andreas W. Schreiber, Neil J. Shirley, Rachel A. B...
BMCBI
2008
169views more  BMCBI 2008»
13 years 10 months ago
CompMoby: Comparative MobyDick for detection of cis-regulatory motifs
Background: The regulation of gene expression is complex and occurs at many levels, including transcriptional and post-transcriptional, in metazoans. Transcriptional regulation is...
Christina Chaivorapol, Collin Melton, Grace Wei, R...
BMCBI
2008
114views more  BMCBI 2008»
13 years 10 months ago
Visualizing and clustering high throughput sub-cellular localization imaging
Background: The expansion of automatic imaging technologies has created a need to be able to efficiently compare and review large sets of image data. To enable comparisons of imag...
Nicholas A. Hamilton, Rohan D. Teasdale
BMCBI
2008
116views more  BMCBI 2008»
13 years 10 months ago
The combination approach of SVM and ECOC for powerful identification and classification of transcription factor
Background: Transcription factors (TFs) are core functional proteins which play important roles in gene expression control, and they are key factors for gene regulation network co...
Guangyong Zheng, Ziliang Qian, Qing Yang, Chaochun...