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» Towards Index-based Similarity Search for Protein Structure ...
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BMCBI
2005
149views more  BMCBI 2005»
13 years 7 months ago
The PD-(D/E)XK superfamily revisited: identification of new members among proteins involved in DNA metabolism and functional pre
Background: The PD-(D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is o...
Jan Kosinski, Marcin Feder, Janusz M. Bujnicki
BMCBI
2004
138views more  BMCBI 2004»
13 years 7 months ago
Constraint Logic Programming approach to protein structure prediction
Background: The protein structure prediction problem is one of the most challenging problems in biological sciences. Many approaches have been proposed using database information ...
Alessandro Dal Palù, Agostino Dovier, Feder...
NAR
2008
103views more  NAR 2008»
13 years 7 months ago
STITCH: interaction networks of chemicals and proteins
The knowledge about interactions between proteins and small molecules is essential for the understanding of molecular and cellular functions. However, information on such interact...
Michael Kuhn 0004, Christian von Mering, Monica Ca...
BMCBI
2002
133views more  BMCBI 2002»
13 years 7 months ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura
EDBT
2012
ACM
257views Database» more  EDBT 2012»
11 years 10 months ago
Indexing and mining topological patterns for drug discovery
Increased availability of large repositories of chemical compounds has created new challenges and opportunities for the application of data-mining and indexing techniques to probl...
Sayan Ranu, Ambuj K. Singh