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BMCBI
2010
131views more  BMCBI 2010»
13 years 2 months ago
Dynamics based alignment of proteins: an alternative approach to quantify dynamic similarity
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
Márton Münz, Rune B. Lyngsø, Jo...
BMCBI
2005
97views more  BMCBI 2005»
13 years 7 months ago
Comparative mapping of sequence-based and structure-based protein domains
Background: Protein domains have long been an ill-defined concept in biology. They are generally described as autonomous folding units with evolutionary and functional independenc...
Ya Zhang, John-Marc Chandonia, Chris H. Q. Ding, S...
BMCBI
2008
140views more  BMCBI 2008»
13 years 7 months ago
SCPRED: Accurate prediction of protein structural class for sequences of twilight-zone similarity with predicting sequences
Background: Protein structure prediction methods provide accurate results when a homologous protein is predicted, while poorer predictions are obtained in the absence of homologou...
Lukasz A. Kurgan, Krzysztof J. Cios, Ke Chen 0003
BCB
2010
125views Bioinformatics» more  BCB 2010»
13 years 2 months ago
Protein structure alignment using elastic shape analysis
In this paper we present a method for flexible protein structure alignment based on elastic shape analysis of backbones, in a manner that can incorporate different characteristics...
Wei Liu, Anuj Srivastava, Jinfeng Zhang
RECOMB
2004
Springer
14 years 7 months ago
Mining protein family specific residue packing patterns from protein structure graphs
Finding recurring residue packing patterns, or spatial motifs, that characterize protein structural families is an important problem in bioinformatics. To this end, we apply a nov...
Jun Huan, Wei Wang 0010, Deepak Bandyopadhyay, Jac...