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BMCBI
2007
138views more  BMCBI 2007»
13 years 7 months ago
A systematic approach to detecting transcription factors in response to environmental stresses
Background: Eukaryotic cells have developed mechanisms to respond to external environmental or physiological changes (stresses). In order to increase the activities of stress-prot...
Li-Hsieh Lin, Hsiao-Ching Lee, Wen-Hsiung Li, Bor-...
BMCBI
2011
12 years 11 months ago
Reconstructing genome-wide regulatory network of E. coli using transcriptome data and predicted transcription factor activities
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...
Yao Fu, Laura R. Jarboe, Julie A. Dickerson
IMSCCS
2006
IEEE
14 years 1 months ago
Combining Comparative Genomics with de novo Motif Discovery to Identify Human Transcription Factor DNA-Binding Motifs
Background: As more and more genomes are sequenced, comparative genomics approaches provide a methodology for identifying conserved regulatory elements that may be involved in gen...
Linyong Mao, W. Jim Zheng
CSB
2005
IEEE
151views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Analysis of SNP-Expression Association Matrices
High throughput expression profiling and genotyping technologies provide the means to study the genetic determinants of population variation in gene expression variation. In this ...
Anya Tsalenko, Roded Sharan, Hege Edvardsen, Vesse...
BMCBI
2008
133views more  BMCBI 2008»
13 years 7 months ago
CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
Matthew S. Hestand, Michiel van Galen, Michel P. V...