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» Transcriptional regulation at a glance
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BMCBI
2007
168views more  BMCBI 2007»
13 years 7 months ago
Bayesian model-based inference of transcription factor activity
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Simon Rogers, Raya Khanin, Mark Girolami
ECCB
2008
IEEE
14 years 2 months ago
SIRENE: supervised inference of regulatory networks
Living cells are the product of gene expression programs that involve the regulated transcription of thousands of genes. The elucidation of transcriptional regulatory networks in ...
Fantine Mordelet, Jean-Philippe Vert
CSB
2005
IEEE
124views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Discovering Functional Transcription Factor Binding from Superimposed Gene Networks
The availability of entire genome sequences, coupled with genome-wide studies of gene expression, offers promise for discovering new pathways along with their regulatory programs....
Matthew T. Weirauch, Joshua M. Stuart
RECOMB
2002
Springer
14 years 7 months ago
From promoter sequence to expression: a probabilistic framework
We present a probabilistic framework that models the process by which transcriptional binding explains the mRNA expression of different genes. Our joint probabilistic model unifie...
Eran Segal, Yoseph Barash, Itamar Simon, Nir Fried...
PPSN
2004
Springer
14 years 26 days ago
Searching Transcriptional Modules Using Evolutionary Algorithms
The mechanism of gene regulation has been studied intensely for decades. It is important to identify synergistic transcriptional motifs. Its search space is so large that an effici...
Je-Gun Joung, Sok June Oh, Byoung-Tak Zhang