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» Transcriptional regulation at a glance
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WABI
2001
Springer
162views Bioinformatics» more  WABI 2001»
13 years 12 months ago
A Simple Hyper-Geometric Approach for Discovering Putative Transcription Factor Binding Sites
A central issue in molecular biology is understanding the regulatory mechanisms that control gene expression. The recent flood of genomic and postgenomic data opens the way for co...
Yoseph Barash, Gill Bejerano, Nir Friedman
RECOMB
2005
Springer
14 years 7 months ago
Causal Inference of Regulator-Target Pairs by Gene Mapping of Expression Phenotypes
Background: Correlations between polymorphic markers and observed phenotypes provide the basis for mapping traits in quantitative genetics. When the phenotype is gene expression, ...
David Kulp, Manjunatha Jagalur
BMCBI
2007
107views more  BMCBI 2007»
13 years 7 months ago
antiCODE: a natural sense-antisense transcripts database
Background: Natural antisense transcripts (NATs) are endogenous RNA molecules that exhibit partial or complete complementarity to other RNAs, and that may contribute to the regula...
Yifei Yin, Yi Zhao, Jie Wang, Changning Liu, Shugu...
BMCBI
2010
118views more  BMCBI 2010»
13 years 7 months ago
Identifying differentially regulated subnetworks from phosphoproteomic data
Background: Various high throughput methods are available for detecting regulations at the level of transcription, translation or posttranslation (e.g. phosphorylation). Integrati...
Martin Klammer, Klaus Godl, Andreas Tebbe, Christo...
NAR
2006
84views more  NAR 2006»
13 years 7 months ago
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
Individual zinc finger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create designer transcription factors and nucleases that are spec...
Jeffrey G. Mandell, Carlos F. Barbas III