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» Transcriptional regulation at a glance
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RECOMB
2005
Springer
14 years 7 months ago
Combinatorial Genetic Regulatory Network Analysis Tools for High Throughput Transcriptomic Data
: A series of genome-scale algorithms and high-performance implementations is described and shown to be useful in the genetic analysis of gene transcription. With them it is possib...
Elissa J. Chesler, Michael A. Langston
BIBE
2007
IEEE
142views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
An HV-SVM Classifier to Infer TF-TF Interactions Using Protein Domains and GO Annotations
—Interactions between transcription factors (TFs) are necessary for deciphering the complex mechanisms of transcription regulation in eukaryotes. In this paper, we proposed a nov...
Xiaoli Li, Jun-Xiang Lee, Bharadwaj Veeravalli, Se...
RECOMB
2004
Springer
14 years 28 days ago
Application of Kernel Method to Reveal Subtypes of TF Binding Motifs
Transcription factor binding sites often contain several subtypes of sequences that follow not just one but several different patterns. We developed a novel sensitive method based ...
Alexander E. Kel, Yuri Tikunov, Nico Voss, Jü...
ISB
2002
140views more  ISB 2002»
13 years 7 months ago
Computer system "Gene Discovery" for promoter structure analysis
Data Mining and Knowledge Discovery techniques proved to be efficient tools for variety of complex tasks in biology including DNA research. This paper presents implementation of th...
Eugenii E. Vityaev, Yuri L. Orlov, Oleg V. Vishnev...
CIBCB
2008
IEEE
14 years 2 months ago
Classification of mouse fRNA genes using evolved neural networks
Functional RNAs (fRNAs) play a key role in gene regulation, at both the transcriptional and translational levels. Identification of fRNA genes can be difficult, given that some cla...
Mars Cheung, Gary B. Fogel