Biological systems have to react to environmental and/or developmental changes by adjusting their biochemical/cellular machinery on numerous levels. In many cases small molecules ...
Lothar Willmitzer, Camila Caldana, Alisdair R. Fer...
Background: One of the challenges of bioinformatics remains the recognition of short signal sequences in genomic DNA such as donor or acceptor splice sites, splicing enhancers or ...
Jens Keilwagen, Jan Grau, Stefan Posch, Ivo Grosse
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
An ad hoc data format is any non-standard, semi-structured data format for which robust data processing tools are not available. In this paper, we present ANNE, a new kind of mark...
For a collection F of d-variate piecewise linear functions of overall combinatorial complexity n, the lower envelope E(F) of F is the pointwise minimum of these functions. The min...