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BMCBI
2010
13 years 7 months ago
2010
Background: Candida albicans is a commonly encountered fungal pathogen in humans. The formation of biofilm is a major virulence factor in C. albicans pathogenesis and is related t...
BMCBI
2010
13 years 7 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
BMCBI
2007
13 years 7 months ago
2007
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
BMCBI
2010
13 years 7 months ago
2010
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
BMCBI
2006
13 years 7 months ago
2006
Background: Analysis of DNA microarray data takes as input spot intensity measurements from scanner software and returns differential expression of genes between two conditions, t...