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BMCBI
2010
96views more  BMCBI 2010»
13 years 10 months ago
OpenChrom: a cross-platform open source software for the mass spectrometric analysis of chromatographic data
Background: Today, data evaluation has become a bottleneck in chromatographic science. Analytical instruments equipped with automated samplers yield large amounts of measurement d...
Philip Wenig, Juergen Odermatt
BMCBI
2010
108views more  BMCBI 2010»
13 years 10 months ago
Confronting two-pair primer design for enzyme-free SNP genotyping based on a genetic algorithm
Background: Polymerase chain reaction with confronting two-pair primers (PCR-CTPP) method produces allelespecific DNA bands of different lengths by adding four designed primers an...
Cheng-Hong Yang, Yu-Huei Cheng, Li-Yeh Chuang, Hsu...
BMCBI
2010
139views more  BMCBI 2010»
13 years 10 months ago
CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site anno
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
Gong-Hua Li, Jing-Fei Huang
BMCBI
2008
98views more  BMCBI 2008»
13 years 10 months ago
GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
Li Shen, Jie Liu, Wei Wang
BMCBI
2008
111views more  BMCBI 2008»
13 years 10 months ago
Probabilistic base calling of Solexa sequencing data
Background: Solexa/Illumina short-read ultra-high throughput DNA sequencing technology produces millions of short tags (up to 36 bases) by parallel sequencing-by-synthesis of DNA ...
Jacques Rougemont, Arnaud Amzallag, Christian Isel...
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