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BMCBI
2010
141views more  BMCBI 2010»
13 years 8 months ago
Computing and visually analyzing mutual information in molecular co-evolution
Background: Selective pressure in molecular evolution leads to uneven distributions of amino acids and nucleotides. In fact one observes correlations among such constituents due t...
Sebastian Bremm, Tobias Schreck, Patrick Boba, Ste...
BMCBI
2007
114views more  BMCBI 2007»
13 years 8 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...
BMCBI
2006
152views more  BMCBI 2006»
13 years 8 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
CTW
2007
121views more  CTW 2007»
13 years 8 months ago
Regularly irregular: how groups reconcile cross-cutting agendas and demand in healthcare
Abstract The flow of technical work in acute healthcare varies unpredictably, in patterns that occur regularly enough that they can be managed. Acute care organizations develop wa...
Christopher P. Nemeth, Mark Nunnally, Michael F. O...
PR
2006
83views more  PR 2006»
13 years 8 months ago
Optimal convex error estimators for classification
A cross-validation error estimator is obtained by repeatedly leaving out some data points, deriving classifiers on the remaining points, computing errors for these classifiers on ...
Chao Sima, Edward R. Dougherty