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    BMCBI
    2010
    128views more  BMCBI 2010»
    Conserved residue clusters at protein-protein interfaces and their use in binding site identification
    13 years 9 months ago
    Conserved residue clusters at protein-protein interfaces and their use in binding site identification
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    Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
    Mainak Guharoy, Pinak Chakrabarti
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    BMCBI
    2008
    136views more  BMCBI 2008»
    GPAT: Retrieval of genomic annotation from large genomic position datasets
    13 years 9 months ago
    GPAT: Retrieval of genomic annotation from large genomic position datasets
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    Background: Recent genome wide transcription factor binding site or chromatin modification mapping analysis techniques, such as chromatin immunoprecipitation (ChIP) linked to DNA ...
    Arnaud Krebs, Mattia Frontini, Làszlò...
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    BMCBI
    2008
    134views more  BMCBI 2008»
    Clustering cancer gene expression data: a comparative study
    13 years 9 months ago
    Clustering cancer gene expression data: a comparative study
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    Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...
    Marcílio Carlos Pereira de Souto, Ivan G. C...
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    BMCBI
    2008
    78views more  BMCBI 2008»
    Genome Environment Browser (GEB): a dynamic browser for visualising high-throughput experimental data in the context of genome f
    13 years 9 months ago
    Genome Environment Browser (GEB): a dynamic browser for visualising high-throughput experimental data in the context of genome f
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    Background: There is accumulating evidence that the milieu of repeat elements and other nongenic sequence features at a given chromosomal locus, here defined as the genome environ...
    Derek Huntley, Y. Amy Tang, Tatyana B. Nesterova, ...
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    BMCBI
    2008
    136views more  BMCBI 2008»
    An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptim
    13 years 9 months ago
    An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptim
    Download  www.biomedcentral.com
    Background: RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categ...
    Alexander Churkin, Danny Barash
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