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BMCBI
2006
239views more  BMCBI 2006»
13 years 7 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
BMCBI
2007
115views more  BMCBI 2007»
13 years 7 months ago
Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
Gabriele Ausiello, Daniele Peluso, Allegra Via, Ma...
SP
2008
IEEE
159views Security Privacy» more  SP 2008»
13 years 7 months ago
Inferring neuronal network connectivity from spike data: A temporal data mining approach
Abstract. Understanding the functioning of a neural system in terms of its underlying circuitry is an important problem in neuroscience. Recent developments in electrophysiology an...
Debprakash Patnaik, P. S. Sastry, K. P. Unnikrishn...

Publication
118views
14 years 9 months ago
The Minimum Circuity Frontier and the Journey to Work
People travel between places of residence and work destinations via transportation net- works. The relation between selection of home and work locations has been heavily debated ...
Levinson, D. and El-Geneidy A.