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BMCBI
2006
160views more  BMCBI 2006»
13 years 9 months ago
MIMAS: an innovative tool for network-based high density oligonucleotide microarray data management and annotation
Background: The high-density oligonucleotide microarray (GeneChip) is an important tool for molecular biological research aiming at large-scale detection of small nucleotide polym...
Leandro Hermida, Olivier Schaad, Philippe Demougin...
BMCBI
2006
174views more  BMCBI 2006»
13 years 9 months ago
CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...
Jing Huang, Wen Wei, Joyce Chen, Jane Zhang, Guoyi...
BMCBI
2006
190views more  BMCBI 2006»
13 years 9 months ago
VANTED: A system for advanced data analysis and visualization in the context of biological networks
Background: Recent advances with high-throughput methods in life-science research have increased the need for automatized data analysis and visual exploration techniques. Sophisti...
Björn H. Junker, Christian Klukas, Falk Schre...
BMCBI
2006
99views more  BMCBI 2006»
13 years 9 months ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
BMCBI
2006
119views more  BMCBI 2006»
13 years 9 months ago
A methodology for the structural and functional analysis of signaling and regulatory networks
Background: Structural analysis of cellular interaction networks contributes to a deeper understanding of network-wide interdependencies, causal relationships, and basic functiona...
Steffen Klamt, Julio Saez-Rodriguez, Jonathan A. L...
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