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BIOINFORMATICS
2011
13 years 2 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj
BMCBI
2011
13 years 2 months ago
A Platform for Processing Expression of Short Time Series (PESTS)
Background: Time course microarray profiles examine the expression of genes over a time domain. They are necessary in order to determine the complete set of genes that are dynamic...
Anshu Sinha, Marianthi Markatou
BMCBI
2011
13 years 2 months ago
Context-dependent transcriptional regulations between signal transduction pathways
Background: Cells coordinate their metabolism, proliferation, and cellular communication according to environmental cues through signal transduction. Because signal transduction h...
Sohyun Hwang, Sangwoo Kim, Heesung Shin, Doheon Le...
BMCBI
2011
13 years 2 months ago
Worm Phenotype Ontology: integrating phenotype data within and beyond the C. elegans community
Background: Caenorhabditis elegans gene-based phenotype information dates back to the 1970’s, beginning with Sydney Brenner and the characterization of behavioral and morphologi...
Gary Schindelman, Jolene Fernandes, Carol Bastiani...
BMCBI
2011
13 years 2 months ago
VennDiagram: a package for the generation of highly-customizable Venn and Euler diagrams in R
Background: Visualization of orthogonal (disjoint) or overlapping datasets is a common task in bioinformatics. Few tools exist to automate the generation of extensively-customizab...
Hanbo Chen, Paul C. Boutros
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