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» Unfolding of Microarray Data
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BMCBI
2004
124views more  BMCBI 2004»
13 years 7 months ago
Tests for finding complex patterns of differential expression in cancers: towards individualized medicine
Background: Microarray studies in cancer compare expression levels between two or more sample groups on thousands of genes. Data analysis follows a population-level approach (e.g....
James Lyons-Weiler, Satish Patel, Michael J. Becic...
BMCBI
2011
13 years 2 months ago
Identifying hypermethylated CpG islands using a quantile regression model
Background: DNA methylation has been shown to play an important role in the silencing of tumor suppressor genes in various tumor types. In order to have a system-wide understandin...
Shuying Sun, Zhengyi Chen, Pearlly Yan, Yi-Wen Hua...
CSB
2005
IEEE
141views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Joint Genomic and Metabolomic Analysis of Toxic Dose-Response Experiments
A methodology has been implemented for analyzing microarray and NMR spectral data obtained from the same set of toxic-exposure dose-response experiments. The NMR spectra additiona...
Gary L. Jahns, Nicholas J. DelRaso, Mark P. Westri...
IDA
2005
Springer
14 years 1 months ago
Biological Cluster Validity Indices Based on the Gene Ontology
With the invention of biotechnological high throughput methods like DNA microarrays and the analysis of the resulting huge amounts of biological data, clustering algorithms gain ne...
Nora Speer, Christian Spieth, Andreas Zell
ISNN
2005
Springer
14 years 1 months ago
Non-parametric Statistical Tests for Informative Gene Selection
This paper presents two non-parametric statistical test methods, called Kolmogorov-Smirnov (KS) and U statistic test methods, respectively, for informative gene selection of a tumo...
Jinwen Ma, Fuhai Li, Jianfeng Liu