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» Unfolding of Microarray Data
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BMCBI
2006
85views more  BMCBI 2006»
13 years 8 months ago
On the statistical assessment of classifiers using DNA microarray data
Background: In this paper we present a method for the statistical assessment of cancer predictors which make use of gene expression profiles. The methodology is applied to a new d...
Nicola Ancona, Rosalia Maglietta, Ada Piepoli, Ann...
BMCBI
2008
125views more  BMCBI 2008»
13 years 8 months ago
MAID : An effect size based model for microarray data integration across laboratories and platforms
Background: Gene expression profiling has the potential to unravel molecular mechanisms behind gene regulation and identify gene targets for therapeutic interventions. As microarr...
Ivan Borozan, Limin Chen, Bryan Paeper, Jenny E. H...
BMCBI
2007
169views more  BMCBI 2007»
13 years 8 months ago
Transcriptional regulatory network refinement and quantification through kinetic modeling, gene expression microarray data and i
Background: Gene expression microarray and other multiplex data hold promise for addressing the challenges of cellular complexity, refined diagnoses and the discovery of well-targ...
Abdallah Sayyed-Ahmad, Kagan Tuncay, Peter J. Orto...
BMCBI
2006
138views more  BMCBI 2006»
13 years 8 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2005
93views more  BMCBI 2005»
13 years 8 months ago
Two-part permutation tests for DNA methylation and microarray data
Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
Markus Neuhäuser, Tanja Boes, Karl-Heinz J&ou...