2749 search results - page 519 / 550 » Usability of interaction patterns |
BMCBI
2010
13 years 9 months ago
2010
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
BMCBI
2010
13 years 9 months ago
2010
Background: Phenomenological information about regulatory interactions is frequently available and can be readily converted to Boolean models. Fully quantitative models, on the ot...
BMCBI
2007
13 years 9 months ago
2007
Background: The ability to visualize genomic features and design experimental assays that can target specific regions of a genome is essential for modern biology. To assist in the...
BMCBI
2007
13 years 9 months ago
2007
Background: Most human genes produce several transcripts with different exon contents by using alternative promoters, alternative polyadenylation sites and alternative splice site...
BMCBI
2007
13 years 9 months ago
2007
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...