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BMCBI
2011
13 years 10 hour ago
2011
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
BMCBI
2011
13 years 10 hour ago
2011
Background: Patterns of genome-wide methylation vary between tissue types. For example, cancer tissue shows markedly different patterns from those of normal tissue. In this paper ...
BMCBI
2011
13 years 10 hour ago
2011
Background: Automated genotype calling in tetraploid species was until recently not possible, which hampered genetic analysis. Modern genotyping assays often produce two signals, ...
BMCBI
2011
13 years 10 hour ago
2011
Background: Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing...
BMCBI
2011
13 years 10 hour ago
2011
Background: While there are many methods for predicting protein-protein interaction, very few can determine the specific site of interaction on each protein. Characterization of t...