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BMCBI
2008
135views more  BMCBI 2008»
13 years 8 months ago
Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...
BMCBI
2008
124views more  BMCBI 2008»
13 years 8 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li
BMCBI
2007
149views more  BMCBI 2007»
13 years 7 months ago
Robust imputation method for missing values in microarray data
Background: When analyzing microarray gene expression data, missing values are often encountered. Most multivariate statistical methods proposed for microarray data analysis canno...
Dankyu Yoon, Eun-Kyung Lee, Taesung Park
BMCBI
2007
132views more  BMCBI 2007»
13 years 7 months ago
Analysis of probe level patterns in Affymetrix microarray data
Background: Microarrays have been used extensively to analyze the expression profiles for thousands of genes in parallel. Most of the widely used methods for analyzing Affymetrix ...
Alexander C. Cambon, Abdelnaby Khalyfa, Nigel G. F...
BMCBI
2006
125views more  BMCBI 2006»
13 years 8 months ago
Evaluating different methods of microarray data normalization
Background: With the development of DNA hybridization microarray technologies, nowadays it is possible to simultaneously assess the expression levels of thousands to tens of thous...
André Fujita, João Ricardo Sato, Leo...