117 search results - page 6 / 24 » Using Hybrid Alignment for Iterative Sequence Database Searc... |
BMCBI
2006
2006
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
13 years 7 months ago
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
MICCAI
2004
Springer
14 years 8 months ago
2004
Springer
Abstract. A new hybrid of feature-based and intensity-based registration is presented. The algorithm reflects a new understanding of the role of alignment error in the generation o...
BMCBI
2010
13 years 7 months ago
2010
Background: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require con...
BMCBI
2007
13 years 7 months ago
2007
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
BMCBI
2011
13 years 2 months ago
2011
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...