Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
—Transcriptional regulation by transcription factors (TFs) and microRNAs controls when and how much RNA is created. Due to technical limitations, the protein level expressions of...
Jia Meng, Hung-I Harry Chen, Jianqiu Zhang, Yidong...
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...