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BMCBI
2010
124views more  BMCBI 2010»
13 years 7 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
JMLR
2010
125views more  JMLR 2010»
13 years 2 months ago
On utility of gene set signatures in gene expression-based cancer class prediction
Machine learning methods that can use additional knowledge in their inference process are central to the development of integrative bioinformatics. Inclusion of background knowled...
Minca Mramor, Marko Toplak, Gregor Leban, Tomaz Cu...
CSB
2005
IEEE
156views Bioinformatics» more  CSB 2005»
14 years 1 months ago
A Robust Meta-classification Strategy for Cancer Diagnosis from Gene Expression Data
One of the major challenges in cancer diagnosis from microarray data is to develop robust classification models which are independent of the analysis techniques used and can combi...
Gabriela Alexe, Gyan Bhanot, Babu Venkataraghavan,...
BMCBI
2011
12 years 11 months ago
Clustering gene expression data with a penalized graph-based metric
Background: The search for cluster structure in microarray datasets is a base problem for the so-called “-omic sciences”. A difficult problem in clustering is how to handle da...
Ariel E. Bayá, Pablo M. Granitto
BMCBI
2007
173views more  BMCBI 2007»
13 years 7 months ago
Recursive Cluster Elimination (RCE) for classification and feature selection from gene expression data
Background: Classification studies using gene expression datasets are usually based on small numbers of samples and tens of thousands of genes. The selection of those genes that a...
Malik Yousef, Segun Jung, Louise C. Showe, Michael...