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BMCBI
2008
13 years 7 months ago
2008
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
BMCBI
2007
13 years 7 months ago
2007
Background: The main two sorts of automatic gene annotation frameworks are ab initio and alignment-based, the latter splitting into two sub-groups. The first group is used for int...
BMCBI
2007
13 years 7 months ago
2007
Background: An adequate and expressive ontological representation of biological organisms and their parts requires formal reasoning mechanisms for their relations of physical aggr...
BMCBI
2007
13 years 7 months ago
2007
Background: Cellular processes depend on the function of intracellular molecular networks. The curation of the literature relevant to specific biological pathways is important for...
BMCBI
2007
13 years 7 months ago
2007
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...