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» Using Multiple Alignments to Improve Gene Prediction
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BMCBI
2004
196views more  BMCBI 2004»
13 years 7 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
BMCBI
2007
128views more  BMCBI 2007»
13 years 7 months ago
Combining classifiers to predict gene function in Arabidopsis thaliana using large-scale gene expression measurements
Background: Arabidopsis thaliana is the model species of current plant genomic research with a genome size of 125 Mb and approximately 28,000 genes. The function of half of these ...
Hui Lan, Rachel Carson, Nicholas J. Provart, Antho...
NAR
2002
82views more  NAR 2002»
13 years 7 months ago
PALS db: Putative Alternative Splicing database
PALS db is a collection of Putative Alternative Splicing information from 19 936 human UniGene clusters and 16 615 mouse UniGene clusters. Alternative splicing (AS) sites were pre...
Y.-H. Huang, Y.-T. Chen, J.-J. Lai, S.-T. Yang, U....
BMCBI
2005
70views more  BMCBI 2005»
13 years 7 months ago
Integrating alternative splicing detection into gene prediction
Background: Alternative splicing (AS) is now considered as a major actor in transcriptome/ proteome diversity and it cannot be neglected in the annotation process of a new genome....
Sylvain Foissac, Thomas Schiex
BMCBI
2004
158views more  BMCBI 2004»
13 years 7 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...