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» Using Multiple Alignments to Improve Gene Prediction
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105
Voted
BMCBI
2007
147views more  BMCBI 2007»
15 years 3 months ago
MaxAlign: maximizing usable data in an alignment
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
Rodrigo Gouveia-Oliveira, Peter Wad Sackett, Ander...
150
Voted
BMCBI
2007
155views more  BMCBI 2007»
15 years 3 months ago
ProCMD: a database and 3D web resource for protein C mutants
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
129
Voted
BMCBI
2006
118views more  BMCBI 2006»
15 years 3 months ago
Automatic generation of gene finders for eukaryotic species
Background: The number of sequenced eukaryotic genomes is rapidly increasing. This means that over time it will be hard to keep supplying customised gene finders for each genome. ...
Kasper Munch, Anders Krogh
120
Voted
BMCBI
2007
111views more  BMCBI 2007»
15 years 3 months ago
Novel definition files for human GeneChips based on GeneAnnot
Background: Improvements in genome sequence annotation revealed discrepancies in the original probeset/gene assignment in Affymetrix microarray and the existence of differences be...
Francesco Ferrari, Stefania Bortoluzzi, Alessandro...
CSB
2002
IEEE
121views Bioinformatics» more  CSB 2002»
15 years 8 months ago
Fast and Sensitive Algorithm for Aligning ESTs to Human Genome
There is a pressing need to align growing set of expressed sequence tags (ESTs) to newly sequenced human genome. The problem is, however, complicated by the exon/intron structure ...
Jun Ogasawara, Shinichi Morishita