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» Using Multiple Alignments to Improve Gene Prediction
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143
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RECOMB
2007
Springer
16 years 4 months ago
Pairwise Global Alignment of Protein Interaction Networks by Matching Neighborhood Topology
We describe an algorithm, IsoRank, for global alignment of two protein-protein interaction (PPI) networks. IsoRank aims to maximize the overall match between the two networks; in c...
Rohit Singh, Jinbo Xu, Bonnie Berger
128
Voted
NIPS
2004
15 years 5 months ago
Probabilistic Inference of Alternative Splicing Events in Microarray Data
Alternative splicing (AS) is an important and frequent step in mammalian gene expression that allows a single gene to specify multiple products, and is crucial for the regulation ...
Ofer Shai, Brendan J. Frey, Quaid Morris, Qun Pan,...
141
Voted
BMCBI
2010
124views more  BMCBI 2010»
15 years 3 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
135
Voted
BMCBI
2005
112views more  BMCBI 2005»
15 years 3 months ago
Towards precise classification of cancers based on robust gene functional expression profiles
Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...
Zheng Guo, Tianwen Zhang, Xia Li, Qi Wang, Jianzhe...
132
Voted
ICS
2011
Tsinghua U.
14 years 7 months ago
Predictive coordination of multiple on-chip resources for chip multiprocessors
Efficient on-chip resource management is crucial for Chip Multiprocessors (CMP) to achieve high resource utilization and enforce system-level performance objectives. Existing mul...
Jian Chen, Lizy Kurian John