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» Using OWL to model biological knowledge
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BMCBI
2007
115views more  BMCBI 2007»
13 years 7 months ago
Comparing sequences without using alignments: application to HIV/SIV subtyping
Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
Gilles Didier, Laurent Debomy, Maude Pupin, Ming Z...
BMCBI
2006
205views more  BMCBI 2006»
13 years 7 months ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch
JBI
2006
117views Bioinformatics» more  JBI 2006»
13 years 7 months ago
Desiderata for domain reference ontologies in biomedicine
Domain reference ontologies represent knowledge about a particular part of the world in a way that is independent from specific objectives, through a theory of the domain. An exam...
Anita Burgun
BMCBI
2010
201views more  BMCBI 2010»
13 years 5 months ago
IntelliGO: a new vector-based semantic similarity measure including annotation origin
Background: The Gene Ontology (GO) is a well known controlled vocabulary describing the biological process, molecular function and cellular component aspects of gene annotation. I...
Sidahmed Benabderrahmane, Malika Smaïl-Tabbon...
BMCBI
2007
128views more  BMCBI 2007»
13 years 7 months ago
Model order selection for bio-molecular data clustering
Background: Cluster analysis has been widely applied for investigating structure in bio-molecular data. A drawback of most clustering algorithms is that they cannot automatically ...
Alberto Bertoni, Giorgio Valentini