Finding similar structures from 3-D structure databases of proteins is becoming more and more important issue in the post-genomic molecular biology. To compare 3-D structures of tw...
Bioinformaticists use the Basic Local Alignment Search Tool (BLAST) to characterize an unknown sequence by comparing it against a database of known sequences, thus detecting evolu...
In this study, a new Genetic Algorithm (GA) using the Tabu · Local Search mechanism is proposed. The GA described in this paper is considered a Mega Process GA, which has an effe...
This paper presents a seed-based algorithm for intensive DNA sequence comparison. The novelty comes from the way seeds are used to efficiently generate small ungapped alignments ...
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...