Background: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but ...
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...
Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
We present a text-based approach for the automatic indexing and retrieval of digital photographs taken at crime scenes. Our research prototype, SOCIS, goes beyond keyword-based ap...
The focus of my thesis is on the development of a multi-method framework for the validation of formal models (domain model, user model, and teaching model) for adaptive work-integr...