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NAR
2006
108views more  NAR 2006»
13 years 7 months ago
GLIDA: GPCR-ligand database for chemical genomic drug discovery
G-protein coupled receptors (GPCRs) represent one of the most important families of drug targets in pharmaceutical development. GPCR-LIgand DAtabase (GLIDA) is a novel public GPCR...
Yasushi Okuno, Jiyoon Yang, Kei Taneishi, Hiroaki ...
BMCBI
2007
156views more  BMCBI 2007»
13 years 7 months ago
Accuracy of structure-based sequence alignment of automatic methods
Background: Accurate sequence alignments are essential for homology searches and for building three-dimensional structural models of proteins. Since structure is better conserved ...
Changhoon Kim, Byungkook Lee
ECWEB
2010
Springer
219views ECommerce» more  ECWEB 2010»
13 years 8 months ago
Semantic Tag Cloud Generation via DBpedia
Abstract. Many current recommender systems exploit textual annotations (tags) provided by users to retrieve and suggest online contents. The text-based recommendation provided by t...
Roberto Mirizzi, Azzurra Ragone, Tommaso Di Noia, ...
BMCBI
2006
82views more  BMCBI 2006»
13 years 7 months ago
Prediction of a key role of motifs binding E2F and NR2F in down-regulation of numerous genes during the development of the mouse
Background: We previously demonstrated that gene expression profiles during neuronal differentiation in vitro and hippocampal development in vivo were very similar, due to a conse...
Michal Dabrowski, Stein Aerts, Bozena Kaminska
ICML
2002
IEEE
14 years 8 months ago
Learning the Kernel Matrix with Semi-Definite Programming
Kernel-based learning algorithms work by embedding the data into a Euclidean space, and then searching for linear relations among the embedded data points. The embedding is perfor...
Gert R. G. Lanckriet, Nello Cristianini, Peter L. ...