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BMCBI
2010
86views more  BMCBI 2010»
13 years 7 months ago
Mining protein loops using a structural alphabet and statistical exceptionality
Background: Protein loops encompass 50% of protein residues in available three-dimensional structures. These regions are often involved in protein functions, e.g. binding site, ca...
Leslie Regad, Juliette Martin, Grégory Nuel...
BIBE
2005
IEEE
14 years 1 months ago
Improved Phylogenetic Motif Detection Using Parsimony
We have recently demonstrated (La et al, Proteins, 58:2005) that sequence fragments approximating the overall familial phylogeny, called phylogenetic motifs (PMs), represent a pro...
Usman Roshan, Dennis R. Livesay, David La
ICML
2007
IEEE
14 years 8 months ago
Structural alignment based kernels for protein structure classification
Structural alignments are the most widely used tools for comparing proteins with low sequence similarity. The main contribution of this paper is to derive various kernels on prote...
Sourangshu Bhattacharya, Chiranjib Bhattacharyya, ...
BMCBI
2007
142views more  BMCBI 2007»
13 years 7 months ago
Predicting and improving the protein sequence alignment quality by support vector regression
Background: For successful protein structure prediction by comparative modeling, in addition to identifying a good template protein with known structure, obtaining an accurate seq...
Minho Lee, Chan-seok Jeong, Dongsup Kim
BMCBI
2008
124views more  BMCBI 2008»
13 years 7 months ago
Alignment of protein structures in the presence of domain motions
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...