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RECOMB
2005
Springer
14 years 8 months ago
Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Cathal Seoighe, Konrad Scheffler
NAR
2002
80views more  NAR 2002»
13 years 8 months ago
Wanda: a database of duplicated fish genes
Comparative genomics has shown that ray-finned fish (Actinopterygii) contain more copies of many genes than other vertebrates. A large number of these additional genes appear to h...
Yves Van de Peer, John Shawe-Taylor, Jayabalan Jos...
RECOMB
2009
Springer
14 years 3 months ago
Reconstructing Histories of Complex Gene Clusters on a Phylogeny
Abstract. Clusters of genes that have evolved by repeated segmental duplication present difficult challenges throughout genomic analysis, from sequence assembly to functional analy...
Tomás Vinar, Brona Brejová, Giltae S...
JCB
2008
102views more  JCB 2008»
13 years 8 months ago
DUPCAR: Reconstructing Contiguous Ancestral Regions with Duplications
Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorit...
Jian Ma, Aakrosh Ratan, Brian J. Raney, Bernard B....
BMCBI
2006
102views more  BMCBI 2006»
13 years 8 months ago
UVPAR: fast detection of functional shifts in duplicate genes
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
Vicente Arnau, Miguel Gallach, J. Ignasi Lucas, Ig...