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BMCBI
2005
253views more  BMCBI 2005»
13 years 7 months ago
The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks
Background: This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated ...
Ruth Dunn, Frank Dudbridge, Christopher M. Sanders...
RECOMB
2003
Springer
14 years 7 months ago
An integrated probabilistic model for functional prediction of proteins
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Minghua Deng, Ting Chen, Fengzhu Sun
BMCBI
2008
124views more  BMCBI 2008»
13 years 7 months ago
Inferring modules of functionally interacting proteins using the Bond Energy Algorithm
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
Ryosuke Watanabe, Enrique Morett, Edgar E. Vallejo
BIBE
2009
IEEE
185views Bioinformatics» more  BIBE 2009»
14 years 14 days ago
Anomaly-free Prediction of Gene Ontology Annotations Using Bayesian Networks
Gene and protein structural and functional annotations expressed through controlled terminologies and ontologies are paramount especially for the aim of inferring new biomedical k...
Marco Tagliasacchi, Marco Masseroli
BMCBI
2006
156views more  BMCBI 2006»
13 years 7 months ago
GOFFA: Gene Ontology For Functional Analysis - A FDA Gene Ontology Tool for Analysis of Genomic and Proteomic Data
Background: Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular componen...
Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins, W...