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BMCBI
2010
172views more  BMCBI 2010»
13 years 7 months ago
Comparison of evolutionary algorithms in gene regulatory network model inference
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Alina Sîrbu, Heather J. Ruskin, Martin Crane
BMCBI
2008
201views more  BMCBI 2008»
13 years 7 months ago
A copula method for modeling directional dependence of genes
Background: Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can b...
Jong-Min Kim, Yoon-Sung Jung, Engin A. Sungur, Kap...
RECOMB
2005
Springer
14 years 7 months ago
Reconstruction of Reticulate Networks from Gene Trees
Abstract. One of the simplest evolutionary models has molecular sequences evolving from a common ancestor down a bifurcating phylogenetic tree, experiencing point-mutations along t...
Daniel H. Huson, Tobias H. Klöpper, Pete J. L...
BMCBI
2010
164views more  BMCBI 2010»
13 years 7 months ago
Gene regulatory networks modelling using a dynamic evolutionary hybrid
Background: Inference of gene regulatory networks is a key goal in the quest for understanding fundamental cellular processes and revealing underlying relations among genes. With ...
Ioannis A. Maraziotis, Andrei Dragomir, Dimitris T...
BMCBI
2008
108views more  BMCBI 2008»
13 years 7 months ago
Empirical methods for controlling false positives and estimating confidence in ChIP-Seq peaks
Background: High throughput signature sequencing holds many promises, one of which is the ready identification of in vivo transcription factor binding sites, histone modifications...
David A. Nix, Samir J. Courdy, Kenneth M. Boucher