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BMCBI
2006
152views more  BMCBI 2006»
13 years 8 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
BMCBI
2008
93views more  BMCBI 2008»
13 years 8 months ago
Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throug
Background: The recent emergence of high-throughput automated image acquisition technologies has forever changed how cell biologists collect and analyze data. Historically, the in...
Zheng Yin, Xiaobo Zhou, Chris Bakal, Fuhai Li, You...
BMCBI
2010
153views more  BMCBI 2010»
13 years 8 months ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
BMCBI
2007
128views more  BMCBI 2007»
13 years 8 months ago
Combining classifiers to predict gene function in Arabidopsis thaliana using large-scale gene expression measurements
Background: Arabidopsis thaliana is the model species of current plant genomic research with a genome size of 125 Mb and approximately 28,000 genes. The function of half of these ...
Hui Lan, Rachel Carson, Nicholas J. Provart, Antho...
EMNLP
2010
13 years 6 months ago
A Semi-Supervised Approach to Improve Classification of Infrequent Discourse Relations Using Feature Vector Extension
Several recent discourse parsers have employed fully-supervised machine learning approaches. These methods require human annotators to beforehand create an extensive training corp...
Hugo Hernault, Danushka Bollegala, Mitsuru Ishizuk...