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» Using probabilistic model checking in systems biology
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CMSB
2009
Springer
14 years 2 months ago
Probabilistic Approximations of Signaling Pathway Dynamics
Systems of ordinary differential equations (ODEs) are often used to model the dynamics of complex biological pathways. We construct a discrete state model as a probabilistic appro...
Bing Liu, P. S. Thiagarajan, David Hsu
ICFEM
2004
Springer
14 years 1 months ago
Linear Inequality LTL (iLTL): A Model Checker for Discrete Time Markov Chains
Abstract. We develop a way of analyzing the behavior of systems modeled using Discrete Time Markov Chains (DTMC). Specifically, we define iLTL, an LTL with linear inequalities on...
YoungMin Kwon, Gul Agha
QEST
2009
IEEE
14 years 2 months ago
The Ins and Outs of the Probabilistic Model Checker MRMC
The Markov Reward Model Checker (MRMC) is a software tool for verifying properties over probabilistic models. It supports PCTL and CSL model checking, and their reward extensions....
Joost-Pieter Katoen, Ivan S. Zapreev, Ernst Moritz...
GECCO
2004
Springer
150views Optimization» more  GECCO 2004»
14 years 1 months ago
Systems Biology Modeling in Human Genetics Using Petri Nets and Grammatical Evolution
Understanding the hierarchical relationships among biochemical, metabolic, and physiological systems in the mapping between genotype and phenotype is expected to improve the diagno...
Jason H. Moore, Lance W. Hahn
WISE
2007
Springer
14 years 2 months ago
Using Ontology with Semantic Web Services to Support Modeling in Systems Biology
Modeling in systems biology is concerned with using experimental information and mathematical methods to build quantitative models at different biological scales. This requires int...
Zhouyang Sun, Anthony Finkelstein, Jonathan Ashmor...