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BMCBI
2010
112views more  BMCBI 2010»
13 years 8 months ago
Knowledge-based analysis of microarrays for the discovery of transcriptional regulation relationships
Background: The large amount of high-throughput genomic data has facilitated the discovery of the regulatory relationships between transcription factors and their target genes. Wh...
Junhee Seok, Amit Kaushal, Ronald W. Davis, Wenzho...
BMCBI
2006
102views more  BMCBI 2006»
13 years 8 months ago
Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of
Background: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the la...
Tao Han, Jianyong Wang, Weida Tong, Martha M. Moor...
EDBT
2012
ACM
257views Database» more  EDBT 2012»
11 years 11 months ago
Indexing and mining topological patterns for drug discovery
Increased availability of large repositories of chemical compounds has created new challenges and opportunities for the application of data-mining and indexing techniques to probl...
Sayan Ranu, Ambuj K. Singh
BMCBI
2006
138views more  BMCBI 2006»
13 years 8 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2002
119views more  BMCBI 2002»
13 years 8 months ago
Microarray results: how accurate are they?
Background: DNA microarray technology is a powerful technique that was recently developed in order to analyze thousands of genes in a short time. Presently, microarrays, or chips,...
Ravi Kothapalli, Sean J. Yoder, Shrikant Mane, Tho...