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IHI
2012
291views Healthcare» more  IHI 2012»
12 years 4 months ago
PANI: an interactive data-driven tool for target prioritization in signaling networks
Biological network analysis often aims at the target identification problem, which is to predict which molecule to inhibit (or activate) for a disease treatment to achieve optimu...
Huey-Eng Chua, Sourav S. Bhowmick, Lisa Tucker-Kel...
BMCBI
2007
143views more  BMCBI 2007»
13 years 8 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
IJSEKE
1998
141views more  IJSEKE 1998»
13 years 8 months ago
REINAS: A Real-Time System for Managing Environmental Data
Managing scientific data is a challenging task, and many of the problems it presents have yet to be adequately solved. The Real-time Environmental Information Network and Analysi...
Eric C. Rosen, Theodore R. Haining, Darrell D. E. ...
BMCBI
2010
129views more  BMCBI 2010»
13 years 8 months ago
A temporal precedence based clustering method for gene expression microarray data
Background: Time-course microarray experiments can produce useful data which can help in understanding the underlying dynamics of the system. Clustering is an important stage in m...
Ritesh Krishna, Chang-Tsun Li, Vicky Buchanan-Woll...
BMCBI
2010
142views more  BMCBI 2010»
13 years 8 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan