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BMCBI
2011
13 years 3 months ago
Implementation of Force Distribution Analysis for Molecular Dynamics simulations
Background: The way mechanical stress is distributed inside and propagated by proteins and other biopolymers largely defines their function. Yet, determining the network of intera...
Wolfram Stacklies, Christian Seifert, Frauke Graet...
GPEM
2000
80views more  GPEM 2000»
13 years 8 months ago
Explanatory Analysis of the Metabolome Using Genetic Programming of Simple, Interpretable Rules
Genetic programming, in conjunction with advanced analytical instruments, is a novel tool for the investigation of complex biological systems at the whole-tissue level. In this stu...
Helen E. Johnson, Richard J. Gilbert, Michael K. W...
HICSS
2003
IEEE
168views Biometrics» more  HICSS 2003»
14 years 1 months ago
'Pay-per-use' Concept in Healthcare: A Grounded Theory Perspective
Healthcare organizations worldwide are faced with the growing challenge of introducing structural and technological reforms and cost-effective IT solutions that will transform the...
Abdullah A. Akbar
BMCBI
2007
158views more  BMCBI 2007»
13 years 8 months ago
Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries
Background: The joint analysis of several categorical variables is a common task in many areas of biology, and is becoming central to systems biology investigations whose goal is ...
Corinne Dahinden, Giovanni Parmigiani, Mark C. Eme...
BMCBI
2010
178views more  BMCBI 2010»
13 years 8 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...