Background: The development of algorithms to infer the structure of gene regulatory networks based on expression data is an important subject in bioinformatics research. Validatio...
Tim Van den Bulcke, Koen Van Leemput, Bart Naudts,...
Background: A molecular network perspective forms the foundation of systems biology. A common practice in analyzing protein-protein interaction (PPI) networks is to perform networ...
In recent years, a few researchers have challenged past dogma and suggested methods (such as the IC algorithm) for inferring causal relationship among variables using steady state ...
The Noise Sensitivity Signature (NSS), originally introduced by Grossman and Lapedes (1993), was proposed as an alternative to cross validation for selecting network complexity. I...
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...